Pooled CRISPR screen optimization tool
10 Stars
Updated Last
4 Years Ago
Started In
April 2016


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A pooled genetic screen simulator

Crispulator does not yet support Julia 1.0! We're still waiting on all the dependencies to be updated, please use Julia v0.6.4 in the mean time.


Pooled screens are very useful, but they are also extraordinarily complex. This work aims to explore the importance of various screen parameters and the relevance of design choices on the downstream analysis and interpretation.


Nagy, T. & Kampmann, M. CRISPulator: a discrete simulation tool for pooled genetic screens. BMC Bioinformatics 18, 347 (2017). (Preprint also available)


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