SCTransform.jl

Single Cell RNA-seq normalization using regularized negative binomial regression
Author rasmushenningsson
Popularity
2 Stars
Updated Last
4 Months Ago
Started In
January 2023

SCTransform.jl

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This is a Julia implementation of sctransform, based on the paper Normalization and variance stabilization of single-cell RNA-seq data using regularized negative binomial regression by Hafemaister and Satija.

This is an independent implementation, the original authors were not involved. Here is the original R implementation of sctransform.

Usage

The doc strings for scparams and sctransform describe the usage. Also see the SingleCellProjections.jl package which provides a framework for working with Single Cell expression data and supports SCTransform.jl.

Note that threading should be enabled in Julia for SCTransform.jl to work optimally.